Abstract

Join us live to discuss the specific challenges associated with the synthesis and manufacture of Highly Potent Active Pharmaceutical Ingredients (HPAPIs) in early process development phases.

We will explain what are HPAPIs, how to categorize them but also how to handle them safely from gram scale to Kg scale. Specific containment strategies, tailored-made equipment, developed at NUVISAN and internal capabilities will be presented with a specific focus on the scale-up from gram to multigram scale production of HPAPIs.

In this 45-minute presentation, Dr. Jean-Guy Boiteau, Head of Chemistry Development, and Dr. Thibaud Gerfaud, Head of Process Research, will cover:

• OEL, PDE & control banding for HPAPIs & their synthetic intermediates at Nuvisan
• Technical solutions for safe handling of HPAPIs at multigram scale during the early process development phases
• Production of HPAPIs at Kg scale
• Live Q&A Session